Incretin Diabetes Drugs Januvia and Janumet May Cause Increased Risk of Pancreatic Cancer: Persons Taking Incretin Diabetes Drugs Should Be Aware of Pancreatic Cancer Risk and Consult Their Physician Regarding Potential Cancer Risks by Texas Januvia Pancreatic Cancer Lawyer, Janumet Pancreatic Cancer Lawyer, and Incretin Drug Cancer Lawyer Jason S. Coomer
Pancreatic cancer kills approximately 40,000 people each year. It is also one of the most deadly of all types of cancer. Further, recent studies show that some incretin diabetes drugs including Januvia and Janumet may cause an increased risk of pancreatic cancer. People on these drugs need to be aware of this cancer health risk. For information on Januvia Pancreatic Cancer Lawsuits, Janumet Pancreatic Cancer Lawsuits, or another Incretin Diabetic Drug Pancreatic Cancer Lawsuit, please feel free to contact Januvia Pancreatic Cancer Lawyer, Januvia Cancer Lawyer, and Januvia Pancreas Cancer Lawyer Jason Coomer a Texas lawyer, or use our online submission form.
Report Incretin Drug Adverse Events to the FDA
The FDA regulates health problems caused by medications. For this reason, please report incidents of pancreatic cancer related to incretin drugs. More specifically, if you take incretin drugs and receive pancreatic cancer diagnosis, report it to the FDA. Further, if you have lost a loved one from pancreatic cancer and they were taking an incretin drug, please report this to the FDA.
The Diabetes Drug Market Rakes In Over $40 Billion Each Year and Growing Rapidly
More than 300 million people worldwide suffer from diabetes. Further, over 30 million Americans suffer from diabetes. More specifically, in 2010, 285 million people had diabetes, by 2030 experts predict this number will increase to 438 million. In the North America, experts say 37.4 million people had diabetes in 2010 and this will increase to 53.2 million by 2030. Further, the numbers in Europe are 55.2 million in 2010 and 66.2 million in 2030. The global market for products in the management of diabetes currently stands at $41 billion. Experts predict the market will grow to over $114 billion by 2018.
Januvia and Janumet produce billions in sales each year. Further, drug companies aggressively compete for market share in the multi billion dollar diabetes drug market. More specifically, annual sales of Januvia rose 39% in 2010 to $3.3 billion. Januvia along with its sister drug Janumet (a combination of Januvia and metformin) combine for billions in sales. Sales of Januvia and Merck's Januvia (sitagliptin) out perform initial estimates for the drugs.
Merck's Januvia (sitagliptin) sells in all major markets. It is the first in a new class of diabetic drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. The FDA allows the drug to be prescribed as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
FDA Provides Information on Sitagliptin (marketed as Januvia and Janumet)
Sitagliptin is an approved incretin diabetic drug. It is in a drug class called dipeptidyl peptidase-4 (DPP-4) inhibitors. It is approved as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Pancreatic Carcinoma, Pancreatic Cancer, and Cancer Pancreas
Pancreatic cancer is the fourth leading cause of cancer death for both men and women. Each year doctors diagnose approximately 45,000 Americans with pancreatic cancer. Further, pancreatic cancer kills about 38,000 people every year.
Unfortunately, people commonly miss early symptoms of pancreatic cancer. Doctors also often fail to diagnose pancreatic cancer. Because pancreatic cancer is hard to detect, doctors commonly diagnose it late. This delay causes many people to miss their chance for early treatment.
Early detection of pancreatic cancer is essential. It greatly improves a person's chances of surviving the disease. As such, people who have taken incretin drugs should be aware of symptoms. More specifically, they need to watch for weight loss, dark urine and clay-colored stools. They should also watch for back pain and jaundice. If these symptoms arise they should seek advice from a qualified medical professional. They should also request a pancreatic cancer screening.
Medical professionals and patients should keep track of any symptoms. They should also track risk factors. Further, doctors should avoid prescribing incretin drugs to people with multiple risk factors.
The Pancreas Releases Enzymes and Helps in the Digestion of Food
The pancreas is a large organ. It is located behind the stomach and in front of the spine above the level of the belly button. This organ performs two main functions: 1) it makes insulin, a hormone that regulates blood sugar levels, and 2) it makes enzymes. More specifically, the pancreas makes and releases enzymes into the intestines that help the body absorb foods. The pancreas is made of Exocrine cells and Endocrine cells. Exocrine cells are cells that produce a pancreatic juice that includes enzymes which aid in the digestion of food in the small intestine, breaking up proteins, carbohydrates, and fats.
Medical Experts Estimate That 90% of Pancreatic Cancer Cases are Pancreatic Adenocarcinoma
The most common type of pancreatic cancer is pancreatic adenocarcinoma. This cancer encompasses about 90% of the cases of pancreatic cancer. Pancreatic adenocarcinoma is a cancerous overgrowth of exocrine pancreatic cells. Doctors commonly miss pancreatic adenocarcinoma, until it is too late for the patient. Pancreatic adenocarcinoma often results in a fatal diagnosis with very limited survival time because of late detection.
Symptoms of Pancreatic Cancer
Medical experts associate several symptoms with pancreatic cancer. They recommend patients who experience these symptoms to seek medical assistance. More specifically, a common symptom of pancreatic cancer includes dark urine and clay-colored stools. Patients also commonly experience fatigue and weakness. They also commonly experience jaundice (a yellow color in the skin, mucus membranes, or eyes). Further, some people suffer loss of appetite and weight loss, nausea and vomiting, and pain or discomfort in the upper part of the belly or abdomen. Other symptoms people experience include back pain, blood clots, diarrhea, and indigestion.
Early Detection of Pancreatic Cancer Helps Survival
Early detection of pancreatic cancer improves survival chances. Unfortunately, many doctors and patients fail to detect early signs of pancreatic cancer. This delay allows the pancreatic cancer to grow and advance prior to detection. As such, medical expert estimate that ninety-five percent of the people diagnosed with this cancer will not be alive 5 years later. However, early detection allows some patients to survive and be cured by having the pancreatic cancer surgically removed.
That being said, late detection commonly prevents a cure and survival. More specifically, in more than 80% of patients the cancer spreads before detection. When this happens, the cancer often becomes too metastasized to remove. In the cases where pancreatic tumors can be removed by surgery, surgeons typically use the Whipple procedure (pancreatoduodenectomy or pancreaticoduodenectomy). This surgery requires an experienced surgeon. The procedure also requires a medical center that performs the procedure often. Some studies suggest that the Whipple procedure is best performed at hospitals that do more than five of these surgeries per year.
Doctors Use Several Drugs and Treatments for Pancreatic Cancer
Doctors use several treatments for pancreatic cancer. These treatments depend on how early the cancer is detected. Early detection requires less aggressive treatment. Whereas late detection requires extremely aggressive treatment, if any at all. Most treatment focuses on removing the cancer or preventing it from spreading. More specifically, doctors commonly use radiation therapy, surgery, and chemotherapy. Medical professionals commonly prescribe the chemotherapy drug is gemcitabine to patients with pancreatic cancer, but other drugs may be used. Gemcitabine helps about 25% of patients.
Medical professionals also work to help manage pain and other symptoms. They use a variety of medications and treatments to manage the pain. These medications and treatments help especially as pancreatic cancer advances. Palliative care tams and hospice help with pain and symptom management. Both provide psychological support for patients and their families during the illness.
Several Problems with the Pancreas Cause Serious Health Issues Including Hemorrhagic Pancreatitis and Necrotizing Pancreatitis
Some people experience acute pancreatitis which occurs when the pancreas becomes suddenly inflamed. During an episode of acute hemorrhagic pancreatitis, patients commonly experience several symptoms relating to digestion. They also commonly experience abdomen pain. Pancreatitis also commonly causes upper abdominal pain that radiates into the back. Patients often describe this pain as a "boring sensation". The pain often becomes more severe when the patient eats foods high in fat. Patients also commonly experience swollen and tender abdomen, fever, nausea and vomiting, and increased heart rate.
In severe cases, the person may experience confusion, difficulty breathing, or respiratory failure. In very severe cases, acute pancreatitis may cause someone to fall into a coma. The severity of acute pancreatitis may range from mild abdominal discomfort to a severe, life-threatening illness. However, the majority of people with acute pancreatitis (more than 80%) recover completely after receiving the appropriate treatment. In very severe cases, acute pancreatitis causes bleeding into the gland, serious tissue damage, infection, and cyst formation. Severe pancreatitis creates conditions which can harm other vital organs such as the heart, lungs, and kidneys. Acute hemorrhagic pancreatitis is the sudden inflammation of the pancreas. This leads to death of pancreatic tissue and the formation of lesions, causing extensive bleeding.
In Necrotizing Pancreatitis patients, there is inflammation and tissue death, with the pancreas destroying itself. Whereas in Hemorrhagic Pancreatitis patients, the pancreas is bleeding. These conditions require immediate medical attention.
Incretin Pancreatic Cancer Lawyers Help Pancreatic Cancer Victims and Families by Filing Lawsuits
Incretin pancreatic cancer lawyers help pancreatic cancer victims. They represent people with pancreatic cancer, if the person took incretin drugs. Further, these lawyers also represent families of those killed by pancreatic cancer and incretin drugs. These lawyers file lawsuits against large drug companies who failed to warn of known risks or dangers of specific incretin drugs. They litigate to prevent additional unnecessary pancreatic cancer deaths and to take dangerous drugs off the market. They also litigate to obtain compensation for the victims and their families.
These incretin pancreatic cancer lawsuits need to be filed within the statute of limitations. For this reason, victims should act as soon as possible to sign up if they want to be involved. Further, families should act within a year or two after the death of a loved one. In some cases and in some states, these statutes may be longer, but all are encouraged to act quickly.
Texas Pancreatic Cancer Lawyer Commonly Works With Other Pancreatic Cancer Lawyers
Texas Diabetes Drug Attorney, Jason Coomer, commonly works with other lawyers throughout the nation. He works with Januvia Pancreatic Cancer Lawyers from throughout the United States. More specifically, he works with California Pancreatic Cancer Attorneys, Georgia Pancreatic Cancer Lawyers, and other Texas Pancreatic Cancer. By sharing information and working together, his law firm provides better representation for his clients.
Januvia Pancreatic Cancer Lawyer and Incretin Pancreatic Cancer Lawyer
If you have lost a loved one from Pancreatic Cancer who was taking an incretin drug, please report this to the prescribing medical doctor. For more information on Januvia Pancreatic Cancer Lawsuits, please feel free to contact Januvia Pancreatic Cancer Lawyer, Janumet Cancer Lawyer, and Incretin Pancreatic Cancer Lawyer Jason Coomer a Texas lawyer, or use our online submission form.
Feel Free to Contact Us with any Questions